- establish a health-based safety standard;
- require the EPA to assess the risk of existing chemicals under "judicially enforceable deadlines", without consideration of cost. This process will include identification of substances on the market, designation of low and high priorities, risk evaluation of high-priority substances, and restrictions for those that present an unreasonable risk;
- strike the existing statute's mandate that the EPA implement "least burdensome" regulatory requirements;
- mandate that the EPA make "an affirmative safety finding" before allowing a new substance on the market, under a 90-day review period (which may be extended to 180 days);
- increases the EPA's authority to order testing, with a requirement to "reduce and replace animal testing where scientifically reliable alternatives exist";
- trigger an EPA review of all past confidential business information (CBI) claims, and require re-substantiation of approved claims after ten years;
- limit state authority to restrict substances that are undergoing EPA review, have been found by the agency not to pose unreasonable risk, or are subject to federal risk management, unless they seek out a waiver. States' authority to require reporting and monitoring are preserved, and chemical restrictions enacted prior to 22 April 2016 are 'grandfathered' in;
- call for identification and protection of most vulnerable populations;
- require science-based decisions, founded on weight of evidence (WoE); and
- collect fees on new and existing chemicals that go directly to the EPA.
Former Printing Caucus Co-Chair Confirmed as Secretary of Labor
On March 10, 2025, the Senate confirmed Lori Chavez-DeRemer as Secretary of the Department of Labor (DOL) by a vote of 67-32. Nearly all Republicans and several Senate Democrats voted to confirm her nomination. Chavez-DeRemer, a former Republican House member representing the 5th Congressional District of Oregon, served as a co-chair of the Congressional Printing Caucus.